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Amino Acid Transporters Are a Vital Focal Point in the Control of mTORC1 Signaling and Cancer

The mechanistic target of rapamycin complex 1 (mTORC1) integrates signals from growth factors and nutrients to control biosynthetic processes, including protein, lipid, and nucleic acid synthesis. Dysregulation in the mTORC1 network underlies a wide array of pathological states, including metabolic...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Cormerais, Yann, Vučetić, Milica, Parks, Scott K., Pouyssegur, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7792758/
https://ncbi.nlm.nih.gov/pubmed/33375025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22010023
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