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Amino Acid Sensing by mTORC1: Intracellular Transporters Mark the Spot

Cell metabolism and growth are matched to nutrient availability via the amino-acid-regulated mechanistic target of rapamycin complex 1 (mTORC1). Transporters have emerged as important amino acid sensors controlling mTOR recruitment and activation at the surface of multiple intracellular compartments...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Goberdhan, Deborah C.I., Wilson, Clive, Harris, Adrian L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067300/
https://ncbi.nlm.nih.gov/pubmed/27076075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.03.013
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