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NaCl cotransporter activity and Mg(2+) handling by the distal convoluted tubule
The genetic disease Gitelman syndrome, knockout mice, and pharmacological blockade with thiazide diuretics have revealed that reduced activity of the NaCl cotransporter (NCC) promotes renal Mg(2+) wasting. NCC is expressed along the distal convoluted tubule (DCT), and its activity determines Mg(2+)...
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| Опубликовано в: : | Am J Physiol Renal Physiol |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Physiological Society
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7792700/ https://ncbi.nlm.nih.gov/pubmed/33135481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00463.2020 |
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