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NaCl cotransporter activity and Mg(2+) handling by the distal convoluted tubule
The genetic disease Gitelman syndrome, knockout mice, and pharmacological blockade with thiazide diuretics have revealed that reduced activity of the NaCl cotransporter (NCC) promotes renal Mg(2+) wasting. NCC is expressed along the distal convoluted tubule (DCT), and its activity determines Mg(2+)...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Am J Physiol Renal Physiol |
|---|---|
| Prif Awduron: | , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
American Physiological Society
2020
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7792700/ https://ncbi.nlm.nih.gov/pubmed/33135481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00463.2020 |
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