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NaCl cotransporter activity and Mg(2+) handling by the distal convoluted tubule
The genetic disease Gitelman syndrome, knockout mice, and pharmacological blockade with thiazide diuretics have revealed that reduced activity of the NaCl cotransporter (NCC) promotes renal Mg(2+) wasting. NCC is expressed along the distal convoluted tubule (DCT), and its activity determines Mg(2+)...
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| Publicado no: | Am J Physiol Renal Physiol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7792700/ https://ncbi.nlm.nih.gov/pubmed/33135481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00463.2020 |
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