PDGF-BB and IL-4 co-overexpression is a potential strategy to enhance mesenchymal stem cell-based bone regeneration

BACKGROUND: Mesenchymal stem cell (MSC)-based therapy has the potential for immunomodulation and enhancement of tissue regeneration. Genetically modified MSCs that over-express specific cytokines, growth factors, or chemokines have shown great promise in pre-clinical studies. In this regard, the ant...

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Bibliografiske detaljer
Udgivet i:Stem Cell Res Ther
Main Authors: Zhang, Ning, Lo, Chi-Wen, Utsunomiya, Takeshi, Maruyama, Masahiro, Huang, Ejun, Rhee, Claire, Gao, Qi, Yao, Zhenyu, Goodman, Stuart B.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7792350/
https://ncbi.nlm.nih.gov/pubmed/33413614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-02086-8
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