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Enzastaurin enhances ATRA-induced differentiation of acute myeloid leukemia cells

All-trans retinoic acid (ATRA) is considered to be the sole clinically-useful differentiating agent in the treatment of acute myeloid leukemia (AML). However, ATRA has been effective only in acute promyelocytic leukemia (APL) but not other subtypes of AML. Therefore, discovering strategies to sensit...

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Bibliografiske detaljer
Udgivet i:Am J Transl Res
Main Authors: Li, Ze-Yi, Liang, Cui, Ding, Ming, Weng, Xiang-Qin, Sheng, Yan, Wu, Jing, Lu, Hao, Cai, Xun
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7791522/
https://ncbi.nlm.nih.gov/pubmed/33437364
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