Enzastaurin enhances ATRA-induced differentiation of acute myeloid leukemia cells

All-trans retinoic acid (ATRA) is considered to be the sole clinically-useful differentiating agent in the treatment of acute myeloid leukemia (AML). However, ATRA has been effective only in acute promyelocytic leukemia (APL) but not other subtypes of AML. Therefore, discovering strategies to sensit...

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Veröffentlicht in:Am J Transl Res
Hauptverfasser: Li, Ze-Yi, Liang, Cui, Ding, Ming, Weng, Xiang-Qin, Sheng, Yan, Wu, Jing, Lu, Hao, Cai, Xun
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2020
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7791522/
https://ncbi.nlm.nih.gov/pubmed/33437364
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