MicroRNA‐146b‐5p overexpression attenuates premature ovarian failure in mice by inhibiting the Dab2ip/Ask1/p38‐Mapk pathway and γH2A.X phosphorylation

OBJECTIVE: To examine the role of high‐fat and high‐sugar (HFHS) diet‐induced oxidative stress, which is a risk factor for various diseases, in premature ovarian failure (POF). MATERIALS AND METHODS: Ovarian granulosa cells (OGCs) were isolated from mice and cultured in medium supplemented with HFHS...

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Publicat a:Cell Prolif
Autors principals: Liu, Te, Lin, Jiajia, Chen, Chuan, Nie, Xiaoli, Dou, Fangfang, Chen, Jiulin, Wang, Zhenxin, Gong, Zhangbin
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7791167/
https://ncbi.nlm.nih.gov/pubmed/33166004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12954
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