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MicroRNA‐146b‐5p overexpression attenuates premature ovarian failure in mice by inhibiting the Dab2ip/Ask1/p38‐Mapk pathway and γH2A.X phosphorylation
OBJECTIVE: To examine the role of high‐fat and high‐sugar (HFHS) diet‐induced oxidative stress, which is a risk factor for various diseases, in premature ovarian failure (POF). MATERIALS AND METHODS: Ovarian granulosa cells (OGCs) were isolated from mice and cultured in medium supplemented with HFHS...
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| Publicado no: | Cell Prolif |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7791167/ https://ncbi.nlm.nih.gov/pubmed/33166004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12954 |
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