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DAB2IP coordinates both PI3K-Akt and ASK1 pathways for cell survival and apoptosis

In metastatic prostate cancer (PCa) cells, imbalance between cell survival and death signals such as constitutive activation of phosphatidylinositol 3-kinase (PI3K)-Akt and inactivation of apoptosis-stimulated kinase (ASK1)-JNK pathways is often detected. Here, we show that DAB2IP protein, often dow...

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Detalhes bibliográficos
Main Authors: Xie, Daxing, Gore, Crystal, Zhou, Jian, Pong, Rey-Chen, Zhang, Haifeng, Yu, Luyang, Vessella, Robert L., Min, Wang, Hsieh, Jer-Tsong
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785260/
https://ncbi.nlm.nih.gov/pubmed/19903888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908458106
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