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DAB2IP coordinates both PI3K-Akt and ASK1 pathways for cell survival and apoptosis
In metastatic prostate cancer (PCa) cells, imbalance between cell survival and death signals such as constitutive activation of phosphatidylinositol 3-kinase (PI3K)-Akt and inactivation of apoptosis-stimulated kinase (ASK1)-JNK pathways is often detected. Here, we show that DAB2IP protein, often dow...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2785260/ https://ncbi.nlm.nih.gov/pubmed/19903888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908458106 |
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