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Preclinical development of CD126 CAR-T cells with broad antitumor activity

Chimeric antigen receptor T (CAR-T) cell therapy is a transformative approach to cancer eradication. CAR-T is expensive partly due to the restricted use of each CAR construct for specific tumors. Thus, a CAR construct with broad antitumor activity can be advantageous. We identified that CD126 is exp...

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Detalhes bibliográficos
Publicado no:Blood Cancer J
Main Authors: Mishra, Ameet K., Kemler, Iris, Dingli, David
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7791061/
https://ncbi.nlm.nih.gov/pubmed/33414408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41408-020-00405-z
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