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Bioorthogonal Chemistry Enables Single-Molecule FRET Measurements of Catalytically Active Protein Disulfide Isomerase

Folding of newly synthesized proteins in the endoplasmic reticulum is assisted by several families of enzymes. One such family is the Protein Disulfide Isomerases (PDIs). PDIs are oxidoreductases, capable of forming new or breaking existing disulfide bonds. Structural information on PDIs unbound and...

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Detalhes bibliográficos
Publicado no:Chembiochem
Main Authors: Chinnaraj, Mathivanan, Barrios, David A., Frieden, Carl, Heyduk, Tomasz, Flaumenhaft, Robert, Pozzi, Nicola
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7790914/
https://ncbi.nlm.nih.gov/pubmed/32857455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.202000537
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