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Bioorthogonal Chemistry Enables Single-Molecule FRET Measurements of Catalytically Active Protein Disulfide Isomerase

Folding of newly synthesized proteins in the endoplasmic reticulum is assisted by several families of enzymes. One such family is the Protein Disulfide Isomerases (PDIs). PDIs are oxidoreductases, capable of forming new or breaking existing disulfide bonds. Structural information on PDIs unbound and...

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Détails bibliographiques
Publié dans:Chembiochem
Auteurs principaux: Chinnaraj, Mathivanan, Barrios, David A., Frieden, Carl, Heyduk, Tomasz, Flaumenhaft, Robert, Pozzi, Nicola
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7790914/
https://ncbi.nlm.nih.gov/pubmed/32857455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.202000537
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