Ophiopogonin D Increases SERCA2a Interaction with Phospholamban by Promoting CYP2J3 Upregulation

Ophiopogonin D (OPD), a compound from the Chinese herb Radix Ophiopogonis, reportedly induces increased levels of cytochrome P450 2J3 (CYP2J3)/epoxyeicosatrienoic acids (EETs) and Ca(2+) in rat cardiomyocytes. Little is known regarding the specific mechanism between CYP2J3 and Ca(2+) homeostasis. He...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Wang, Jia, You, Wenting, Wang, Ningning, Zhou, Wei, Ge, Yunxuan, Ma, Zengchun, Tan, Hongling, Wang, Yuguang, Gao, Yue
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7790559/
https://ncbi.nlm.nih.gov/pubmed/33488937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8857906
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