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Multi-scale modeling of macrophage—T cell interactions within the tumor microenvironment

Within the tumor microenvironment, macrophages exist in an immunosuppressive state, preventing T cells from eliminating the tumor. Due to this, research is focusing on immunotherapies that specifically target macrophages in order to reduce their immunosuppressive capabilities and promote T cell func...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Cess, Colin G., Finley, Stacey D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7790427/
https://ncbi.nlm.nih.gov/pubmed/33362239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008519
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