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Mathematical modeling of tumor-associated macrophage interactions with the cancer microenvironment

BACKGROUND: Immuno-oncotherapy has emerged as a promising means to target cancer. In particular, therapeutic manipulation of tumor-associated macrophages holds promise due to their various and sometimes opposing roles in tumor progression. It is established that M1-type macrophages suppress tumor pr...

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Publicado en:J Immunother Cancer
Autores principales: Mahlbacher, Grace, Curtis, Louis T., Lowengrub, John, Frieboes, Hermann B.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791333/
https://ncbi.nlm.nih.gov/pubmed/29382395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-017-0313-7
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