Only Hyperuricemia with Crystalluria, but not Asymptomatic Hyperuricemia, Drives Progression of Chronic Kidney Disease

BACKGROUND: The roles of asymptomatic hyperuricemia or uric acid (UA) crystals in CKD progression are unknown. Hypotheses to explain links between UA deposition and progression of CKD include that (1) asymptomatic hyperuricemia does not promote CKD progression unless UA crystallizes in the kidney; (...

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Foilsithe in:J Am Soc Nephrol
Main Authors: Sellmayr, Markus, Hernandez Petzsche, Moritz Roman, Ma, Qiuyue, Krüger, Nils, Liapis, Helen, Brink, Andreas, Lenz, Barbara, Angelotti, Maria Lucia, Gnemmi, Viviane, Kuppe, Christoph, Kim, Hyojin, Bindels, Eric Moniqué Johannes, Tajti, Ferenc, Saez-Rodriguez, Julio, Lech, Maciej, Kramann, Rafael, Romagnani, Paola, Anders, Hans-Joachim, Steiger, Stefanie
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Nephrology 2020
Ábhair:
Basic Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7790211/
https://ncbi.nlm.nih.gov/pubmed/32938648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2020040523
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