Only Hyperuricemia with Crystalluria, but not Asymptomatic Hyperuricemia, Drives Progression of Chronic Kidney Disease

BACKGROUND: The roles of asymptomatic hyperuricemia or uric acid (UA) crystals in CKD progression are unknown. Hypotheses to explain links between UA deposition and progression of CKD include that (1) asymptomatic hyperuricemia does not promote CKD progression unless UA crystallizes in the kidney; (...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Sellmayr, Markus, Hernandez Petzsche, Moritz Roman, Ma, Qiuyue, Krüger, Nils, Liapis, Helen, Brink, Andreas, Lenz, Barbara, Angelotti, Maria Lucia, Gnemmi, Viviane, Kuppe, Christoph, Kim, Hyojin, Bindels, Eric Moniqué Johannes, Tajti, Ferenc, Saez-Rodriguez, Julio, Lech, Maciej, Kramann, Rafael, Romagnani, Paola, Anders, Hans-Joachim, Steiger, Stefanie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2020
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7790211/
https://ncbi.nlm.nih.gov/pubmed/32938648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2020040523
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