Polygenic overlap and shared genetic loci between loneliness, severe mental disorders, and cardiovascular disease risk factors suggest shared molecular mechanisms

Clinical and epidemiological evidence suggest that loneliness is associated with severe mental disorders (SMDs) and increases the risk of cardiovascular disease (CVD). However, the mechanisms underlying the relationship between loneliness, SMDs, and CVD risk factors remain unknown. Here we explored...

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Udgivet i:Transl Psychiatry
Main Authors: Rødevand, Linn, Bahrami, Shahram, Frei, Oleksandr, Lin, Aihua, Gani, Osman, Shadrin, Alexey, Smeland, Olav B., Connell, Kevin S. O’, Elvsåshagen, Torbjørn, Winterton, Adriano, Quintana, Daniel S., Hindley, Guy F. L., Werner, Maren C. F., Djurovic, Srdjan, Dale, Anders M., Lagerberg, Trine V., Steen, Nils Eiel, Andreassen, Ole A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7790035/
https://ncbi.nlm.nih.gov/pubmed/33414458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-020-01142-4
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