Extensive bidirectional genetic overlap between bipolar disorder and cardiovascular disease phenotypes

Patients with bipolar disorder (BIP) have a high risk of cardiovascular disease (CVD), despite considerable individual variation. The mechanisms underlying comorbid CVD in BIP remain largely unknown. We investigated polygenic overlap between BIP and CVD phenotypes, including CVD risk factors and cor...

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Vydáno v:Transl Psychiatry
Hlavní autoři: Rødevand, Linn, Bahrami, Shahram, Frei, Oleksandr, Chu, Yunhan, Shadrin, Alexey, O’Connell, Kevin S., Smeland, Olav B., Elvsåshagen, Torbjørn, Hindley, Guy F. L., Djurovic, Srdjan, Dale, Anders M., Lagerberg, Trine V., Steen, Nils Eiel, Andreassen, Ole A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8302675/
https://ncbi.nlm.nih.gov/pubmed/34301917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-021-01527-z
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