Extensive bidirectional genetic overlap between bipolar disorder and cardiovascular disease phenotypes

Patients with bipolar disorder (BIP) have a high risk of cardiovascular disease (CVD), despite considerable individual variation. The mechanisms underlying comorbid CVD in BIP remain largely unknown. We investigated polygenic overlap between BIP and CVD phenotypes, including CVD risk factors and cor...

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Udgivet i:Transl Psychiatry
Main Authors: Rødevand, Linn, Bahrami, Shahram, Frei, Oleksandr, Chu, Yunhan, Shadrin, Alexey, O’Connell, Kevin S., Smeland, Olav B., Elvsåshagen, Torbjørn, Hindley, Guy F. L., Djurovic, Srdjan, Dale, Anders M., Lagerberg, Trine V., Steen, Nils Eiel, Andreassen, Ole A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8302675/
https://ncbi.nlm.nih.gov/pubmed/34301917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-021-01527-z
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