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Protein kinase A catalytic-α and catalytic-β proteins have nonredundant regulatory functions

Vasopressin regulates osmotic water transport in the renal collecting duct by protein kinase A (PKA)-mediated control of the water channel aquaporin-2 (AQP2). Collecting duct principal cells express two seemingly redundant PKA catalytic subunits, PKA catalytic α (PKA-Cα) and PKA catalytic β (PKA-Cβ)...

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Publicat a:Am J Physiol Renal Physiol
Autors principals: Raghuram, Viswanathan, Salhadar, Karim, Limbutara, Kavee, Park, Euijung, Yang, Chin-Rang, Knepper, Mark A.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7789987/
https://ncbi.nlm.nih.gov/pubmed/33017189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00383.2020
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