Non-purine selective xanthine oxidase inhibitor ameliorates glomerular endothelial injury in Ins(Akita) diabetic mice

Endothelial dysfunction represents a predominant early feature of diabetes, rendering patients with diabetes prone to renal complications, e.g., proteinuria. Recent studies have indicated a possible role for xanthine oxidase (XO) in the pathogenesis of vascular dysfunctions associated with diabetes....

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Gepubliceerd in:Am J Physiol Renal Physiol
Hoofdauteurs: Itano, Seiji, Kadoya, Hiroyuki, Satoh, Minoru, Nakamura, Takashi, Murase, Takayo, Sasaki, Tamaki, Kanwar, Yashpal S., Kashihara, Naoki
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2020
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7789983/
https://ncbi.nlm.nih.gov/pubmed/32954851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00236.2020
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