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Amelioration of progressive renal injury by genetic manipulation of Klotho gene
Klotho, an antiaging gene with restricted organ distribution, is mainly expressed in the kidney tubules; the mutant mice have shortened life span, arteriosclerosis, anemia, and osteoporesis, features common to patients with chronic renal failure. Conceivably, the reduction of the Klotho gene express...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1892974/ https://ncbi.nlm.nih.gov/pubmed/17287345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611079104 |
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