Activation of endothelial NAD(P)H oxidase accelerates early glomerular injury in diabetic mice

Increased generation of reactive oxygen species (ROS) is a common denominative pathogenic mechanism underlying vascular and renal complications in diabetes mellitus. Endothelial NAD(P)H oxidase is a major source of vascular ROS, and it has an important role in endothelial dysfunction. We hypothesize...

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Detalhes bibliográficos
Publicado no:Lab Invest
Main Authors: Nagasu, Hajime, Satoh, Minoru, Kiyokage, Emi, Kidokoro, Kengo, Toida, Kazunori, Channon, Keith M, Kanwar, Yashpal S, Sasaki, Tamaki, Kashihara, Naoki
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874489/
https://ncbi.nlm.nih.gov/pubmed/26552047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2015.128
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