Serum HBV RNA correlated with intrahepatic cccDNA more strongly than other HBV markers during peg-interferon treatment

BACKGROUND: Serum hepatitis B virus RNA (HBV RNA) has been reported to be a surrogate marker of intrahepatic cccDNA during nucleos(t)ide analogs therapy. However, in HBeAg-positive patients treated with peg-interferon (peg-IFN), whether HBV RNA is superior to other HBV markers in reflecting cccDNA p...

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Veröffentlicht in:Virol J
Hauptverfasser: Wang, Xiaomei, Chi, Xiumei, Wu, Ruihong, Xu, Hongqin, Gao, Xiuzhu, Yu, Lei, Liu, Longgen, Zhang, Mingxiang, Tan, Youwen, Niu, Junqi, Jin, Qinglong
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7789711/
https://ncbi.nlm.nih.gov/pubmed/33407619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-020-01471-2
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