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Serum HBV RNA composition dynamics as a marker for intrahepatic HBV cccDNA turnover

Current therapies can suppress the replication of hepatitis B virus (HBV) but cannot clear chronic HBV infection, which afflicts hundreds of millions worldwide. HBV persistence is sustained by the viral covalently closed circular DNA (cccDNA), an episome in the nucleus of infected hepatocytes. cccDN...

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Detalhes bibliográficos
Publicado no:J Med Virol
Main Authors: Hong, Xupeng, Hu, Jianming
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7379877/
https://ncbi.nlm.nih.gov/pubmed/32320077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmv.25925
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