A novel immune classification reveals distinct immune escape mechanism and genomic alterations: implications for immunotherapy in hepatocellular carcinoma

BACKGROUND: The tumor immunological microenvironment (TIME) has a prominent impact on prognosis and immunotherapy. However, the heterogeneous TIME and the mechanisms by which TIME affects immunotherapy have not been elucidated in hepatocellular carcinoma (HCC). METHODS: A total of 2195 eligible HCC...

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Publicat a:J Transl Med
Autors principals: Liu, Zaoqu, Zhang, Yuyuan, Shi, Chengcheng, Zhou, Xueliang, Xu, Kaihao, Jiao, Dechao, Sun, Zhenqiang, Han, Xinwei
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7789239/
https://ncbi.nlm.nih.gov/pubmed/33407585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-020-02697-y
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