A novel immune classification reveals distinct immune escape mechanism and genomic alterations: implications for immunotherapy in hepatocellular carcinoma

BACKGROUND: The tumor immunological microenvironment (TIME) has a prominent impact on prognosis and immunotherapy. However, the heterogeneous TIME and the mechanisms by which TIME affects immunotherapy have not been elucidated in hepatocellular carcinoma (HCC). METHODS: A total of 2195 eligible HCC...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Transl Med
Auteurs principaux: Liu, Zaoqu, Zhang, Yuyuan, Shi, Chengcheng, Zhou, Xueliang, Xu, Kaihao, Jiao, Dechao, Sun, Zhenqiang, Han, Xinwei
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2021
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7789239/
https://ncbi.nlm.nih.gov/pubmed/33407585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-020-02697-y
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