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Retinol from hepatic stellate cells via STRA6 induces lipogenesis on hepatocytes during fibrosis
BACKGROUND: Hepatic stellate cells (HSCs) are activated in response to liver injury with TIF1γ-suppression, leading to liver fibrosis. Here, we examined the mechanism how reduction of TIF1γ in HSCs induces damage on hepatocytes and liver fibrosis. METHOD: Lrat:Cas9-ERT2:sgTif1γ mice were treated Tam...
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| Publicat a: | Cell Biosci |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7789180/ https://ncbi.nlm.nih.gov/pubmed/33407858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-020-00509-w |
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