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Transthyretin Blocks Retinol Uptake and Cell Signaling by the Holo-Retinol-Binding Protein Receptor STRA6

Vitamin A is secreted from cellular stores and circulates in blood bound to retinol-binding protein (RBP). In turn, holo-RBP associates in plasma with transthyretin (TTR) to form a ternary RBP-retinol-TTR complex. It is believed that binding to TTR prevents the loss of RBP by filtration in the kidne...

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Hlavní autoři: Berry, Daniel C., Croniger, Colleen M., Ghyselinck, Norbert B., Noy, Noa
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457529/
https://ncbi.nlm.nih.gov/pubmed/22826435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00775-12
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