Genome-wide occupancy reveals the localization of H1T2 (H1fnt) to repeat regions and a subset of transcriptionally active chromatin domains in rat spermatids

BACKGROUND: H1T2/H1FNT is a germ cell-specific linker histone variant expressed during spermiogenesis specifically in round and elongating spermatids. Infertile phenotype of homozygous H1T2 mutant male mice revealed the essential function of H1T2 for the DNA condensation and histone-to-protamine rep...

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Vydáno v:Epigenetics Chromatin
Hlavní autoři: Shalini, Vasantha, Bhaduri, Utsa, Ravikkumar, Anjhana C., Rengarajan, Anusha, Satyanarayana, Rao M. R.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7788777/
https://ncbi.nlm.nih.gov/pubmed/33407810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-020-00376-2
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