Spermatid-specific linker histone HILS1 is a poor condenser of DNA and chromatin and preferentially associates with LINE-1 elements

BACKGROUND: Linker histones establish and maintain higher-order chromatin structure. Eleven linker histone subtypes have been reported in mammals. HILS1 is a spermatid-specific linker histone, and its expression overlaps with the histone–protamine exchange process during mammalian spermiogenesis. Ho...

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Detalhes bibliográficos
Publicado no:Epigenetics Chromatin
Main Authors: Mishra, Laxmi Narayan, Shalini, Vasantha, Gupta, Nikhil, Ghosh, Krittika, Suthar, Neeraj, Bhaduri, Utsa, Rao, M. R. Satyanarayana
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6069787/
https://ncbi.nlm.nih.gov/pubmed/30068355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-018-0214-0
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