Spermatid-specific linker histone HILS1 is a poor condenser of DNA and chromatin and preferentially associates with LINE-1 elements

BACKGROUND: Linker histones establish and maintain higher-order chromatin structure. Eleven linker histone subtypes have been reported in mammals. HILS1 is a spermatid-specific linker histone, and its expression overlaps with the histone–protamine exchange process during mammalian spermiogenesis. Ho...

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Vydáno v:Epigenetics Chromatin
Hlavní autoři: Mishra, Laxmi Narayan, Shalini, Vasantha, Gupta, Nikhil, Ghosh, Krittika, Suthar, Neeraj, Bhaduri, Utsa, Rao, M. R. Satyanarayana
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6069787/
https://ncbi.nlm.nih.gov/pubmed/30068355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-018-0214-0
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