Ectonucleotidase CD39 is highly expressed on ATLL cells and is responsible for their immunosuppressive function

Adult T-cell leukemia/lymphoma (ATLL) patients have an extremely poor prognosis, partly due to their immunosuppressive state. The majority of ATLL patients have leukemic cells with phenotype similar to Tregs, prompting suggestions that ATLL cells themselves have immunosuppressive functions. In this...

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Dades bibliogràfiques
Publicat a:Leukemia
Autors principals: Nagate, Yasuhiro, Ezoe, Sachiko, Fujita, Jiro, Okuzaki, Daisuke, Motooka, Daisuke, Ishibashi, Tomohiko, Ichii, Michiko, Tanimura, Akira, Kurashige, Masako, Morii, Eiichi, Fukushima, Takuya, Suehiro, Youko, Yokota, Takafumi, Shibayama, Hirohiko, Oritani, Kenji, Kanakura, Yuzuru
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7787980/
https://ncbi.nlm.nih.gov/pubmed/32203145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-020-0788-y
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