Autonomous TGFβ signaling induces phenotypic variation in human acute myeloid leukemia

Heterogeneity of leukemia stem cells (LSCs) is involved in their collective chemoresistance. To eradicate LSCs, it is necessary to understand the mechanisms underlying their heterogeneity. Here, we aimed to identify signals responsible for heterogeneity and variation of LSCs in human acute myeloid l...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Shingai, Yasuhiro, Yokota, Takafumi, Okuzaki, Daisuke, Sudo, Takao, Ishibashi, Tomohiko, Doi, Yukiko, Ueda, Tomoaki, Ozawa, Takayuki, Nakai, Ritsuko, Tanimura, Akira, Ichii, Michiko, Shibayama, Hirohiko, Kanakura, Yuzuru, Hosen, Naoki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2021
Assuntos:
Cancer Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8248163/
https://ncbi.nlm.nih.gov/pubmed/33539590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3348
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