Autonomous TGFβ signaling induces phenotypic variation in human acute myeloid leukemia

Heterogeneity of leukemia stem cells (LSCs) is involved in their collective chemoresistance. To eradicate LSCs, it is necessary to understand the mechanisms underlying their heterogeneity. Here, we aimed to identify signals responsible for heterogeneity and variation of LSCs in human acute myeloid l...

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Bibliografiska uppgifter
I publikationen:Stem Cells
Huvudupphovsmän: Shingai, Yasuhiro, Yokota, Takafumi, Okuzaki, Daisuke, Sudo, Takao, Ishibashi, Tomohiko, Doi, Yukiko, Ueda, Tomoaki, Ozawa, Takayuki, Nakai, Ritsuko, Tanimura, Akira, Ichii, Michiko, Shibayama, Hirohiko, Kanakura, Yuzuru, Hosen, Naoki
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley & Sons, Inc. 2021
Ämnen:
Cancer Stem Cells
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8248163/
https://ncbi.nlm.nih.gov/pubmed/33539590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3348
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