Tumor Cell-Secreted ISG15 Promotes Tumor Cell Migration and Immune Suppression by Inducing the Macrophage M2-Like Phenotype

Interferon-stimulated gene 15 (ISG15) is known to be involved in tumor progression. We previously reported that ISG15 expressed on nasopharyngeal carcinoma (NPC) cells and related to poor prognosis of patients with NPC. We further observed that ISG15 can be secreted by NPC cell and expressed on the...

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Vydáno v:Front Immunol
Hlavní autoři: Chen, Ren-Hui, Xiao, Zhi-Wen, Yan, Xiao-Qing, Han, Ping, Liang, Fa-Ya, Wang, Jing-Yi, Yu, Shi-Tong, Zhang, Ting-Zhen, Chen, Si-Qi, Zhong, Qian, Huang, Xiao-Ming
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7785797/
https://ncbi.nlm.nih.gov/pubmed/33424843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.594775
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