ISG15 as a Novel Tumor Biomarker for Drug Sensitivity

Tumor cells are known to exhibit highly varied sensitivity to CPTs (e.g. irinotecan and topotecan). However, the factors that determine CPT sensitivity/resistance are largely unknown. Recent studies have shown that the ubiquitin-like protein, ISG15 (Interferon-Stimulated Gene 15), which is highly el...

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Detalhes bibliográficos
Main Authors: Desai, Shyamal D., Wood, Laurence M., Tsai, Yu-Chen, Hsieh, Tao-Shih, Marks, Jeffrey R., Scott, Georgia L, Giovanella, Beppino C., Liu, Leroy F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2561335/
https://ncbi.nlm.nih.gov/pubmed/18566215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-07-2345
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