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ISG15 Deregulates Autophagy in Genotoxin-treated Ataxia Telangiectasia Cells

Ataxia-telangiectasia (A-T) is a cerebellar neurodegenerative disorder; however, the basis for the neurodegeneration in A-T is not well established. Lesions in the ubiquitin and autophagy pathways are speculated to contribute to the neurodegeneration in other neurological diseases and may have a rol...

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Detalhes bibliográficos
Main Authors: Desai, Shyamal D., Reed, Ryan E., Babu, Shilka, Lorio, Eric A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554909/
https://ncbi.nlm.nih.gov/pubmed/23212917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.403832
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