Maf1 Ameliorates Sepsis-Associated Encephalopathy by Suppressing the NF-kB/NLRP3 Inflammasome Signaling Pathway

BACKGROUND: The NOD-, LRR- and pyrin domain-containing protein 3 (NLRP3) inflammasome has been identified as an important mediator of blood–brain-barrier disruption in sepsis-associated encephalopathy (SAE). However, no information is available concerning the critical upstream regulators of SAE. MET...

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Bibliografske podrobnosti
izdano v:Front Immunol
Main Authors: Chen, Shenglong, Tang, Chaogang, Ding, Hongguang, Wang, Zhonghua, Liu, Xinqiang, Chai, Yunfei, Jiang, Wenqiang, Han, Yongli, Zeng, Hongke
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7785707/
https://ncbi.nlm.nih.gov/pubmed/33424842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.594071
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