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Elevated intracranial pressure induces IL-1β and IL-18 overproduction via activation of the NLRP3 inflammasome in microglia of ischemic adult rats

Elevated intracranial pressure (ICP) is one of the most common complications following an ischemic stroke, and has implications for the clinical and neurological outcomes. The aim of the present study was to examine whether elevated ICP may increase IL-1β and IL-18 secretion by activating the NOD-li...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Med
Hauptverfasser: Ding, Hongguang, Li, Ya, Wen, Miaoyun, Liu, Xinqiang, Han, Yongli, Zeng, Hongke
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7723509/
https://ncbi.nlm.nih.gov/pubmed/33236152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2020.4779
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