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Elevated intracranial pressure induces IL-1β and IL-18 overproduction via activation of the NLRP3 inflammasome in microglia of ischemic adult rats

Elevated intracranial pressure (ICP) is one of the most common complications following an ischemic stroke, and has implications for the clinical and neurological outcomes. The aim of the present study was to examine whether elevated ICP may increase IL-1β and IL-18 secretion by activating the NOD-li...

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Bibliografiska uppgifter
I publikationen:Int J Mol Med
Huvudupphovsmän: Ding, Hongguang, Li, Ya, Wen, Miaoyun, Liu, Xinqiang, Han, Yongli, Zeng, Hongke
Materialtyp: Artigo
Språk:Inglês
Publicerad: D.A. Spandidos 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7723509/
https://ncbi.nlm.nih.gov/pubmed/33236152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2020.4779
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