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Extracellular matrix-bound FGF2 mediates estrogen receptor signaling and therapeutic response in breast cancer

The extracellular matrix (ECM) is often unaccounted for in studies that consider the stromal contribution to cancer cell signaling and response to treatment. To investigate the influence of a fibrotic microenvironment we utilize fibroblast-derived ECM scaffolds as a cell culture platform. We uncover...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Mol Cancer Res
Asıl Yazarlar: DiGiacomo, Josh W., Godet, Inês, Trautmann-Rodriguez, Michael, Gilkes, Daniele M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7785668/
https://ncbi.nlm.nih.gov/pubmed/33033110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-20-0554
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