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Hypoxia and the extracellular matrix: drivers of tumour metastasis

Of the deaths attributed to cancer, 90% are due to metastasis, and treatments that prevent or cure metastasis remain elusive. Emerging data indicate that hypoxia and the extracellular matrix (ECM) might have crucial roles in metastasis. During tumour evolution, changes in the composition and the ove...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Rev Cancer
Prif Awduron: Gilkes, Daniele M., Semenza, Gregg L., Wirtz, Denis
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4283800/
https://ncbi.nlm.nih.gov/pubmed/24827502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3726
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