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Hypoxia and the extracellular matrix: drivers of tumour metastasis

Of the deaths attributed to cancer, 90% are due to metastasis, and treatments that prevent or cure metastasis remain elusive. Emerging data indicate that hypoxia and the extracellular matrix (ECM) might have crucial roles in metastasis. During tumour evolution, changes in the composition and the ove...

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Dades bibliogràfiques
Publicat a:Nat Rev Cancer
Autors principals: Gilkes, Daniele M., Semenza, Gregg L., Wirtz, Denis
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4283800/
https://ncbi.nlm.nih.gov/pubmed/24827502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3726
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