Using machine learning algorithms to predict immunotherapy response in patients with advanced melanoma

PURPOSE: Several biomarkers of response to immune checkpoint inhibitors (ICIs) show potential but are not yet scalable to the clinic. We developed a pipeline that integrates deep learning on histology specimens with clinical data to predict ICI response in advanced melanoma. EXPERIMENTAL DESIGN: We...

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Publicado en:Clin Cancer Res
Main Authors: Johannet, Paul, Coudray, Nicolas, Donnelly, Douglas M., Jour, George, Bochaca, Irineu Illa, Xia, Yuhe, Johnson, Douglas B., Wheless, Lee, Patrinely, James R., Nomikou, Sofia, Rimm, David L., Pavlick, Anna C., Weber, Jeffrey S., Zhong, Judy, Tsirigos, Aristotelis, Osman, Iman
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7785656/
https://ncbi.nlm.nih.gov/pubmed/33208341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-2415
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