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Relating the gut metagenome and metatranscriptome to immunotherapy responses in melanoma patients

BACKGROUND: Recent evidence suggests that immunotherapy efficacy in melanoma is modulated by gut microbiota. Few studies have examined this phenomenon in humans, and none have incorporated metatranscriptomics, important for determining expression of metagenomic functions in the microbial community....

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Pubblicato in:Genome Med
Autori principali: Peters, Brandilyn A., Wilson, Melissa, Moran, Una, Pavlick, Anna, Izsak, Allison, Wechter, Todd, Weber, Jeffrey S., Osman, Iman, Ahn, Jiyoung
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6785875/
https://ncbi.nlm.nih.gov/pubmed/31597568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-019-0672-4
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