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Relating the gut metagenome and metatranscriptome to immunotherapy responses in melanoma patients

BACKGROUND: Recent evidence suggests that immunotherapy efficacy in melanoma is modulated by gut microbiota. Few studies have examined this phenomenon in humans, and none have incorporated metatranscriptomics, important for determining expression of metagenomic functions in the microbial community....

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Publicado en:Genome Med
Main Authors: Peters, Brandilyn A., Wilson, Melissa, Moran, Una, Pavlick, Anna, Izsak, Allison, Wechter, Todd, Weber, Jeffrey S., Osman, Iman, Ahn, Jiyoung
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6785875/
https://ncbi.nlm.nih.gov/pubmed/31597568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-019-0672-4
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