Using machine learning algorithms to predict immunotherapy response in patients with advanced melanoma

PURPOSE: Several biomarkers of response to immune checkpoint inhibitors (ICIs) show potential but are not yet scalable to the clinic. We developed a pipeline that integrates deep learning on histology specimens with clinical data to predict ICI response in advanced melanoma. EXPERIMENTAL DESIGN: We...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Johannet, Paul, Coudray, Nicolas, Donnelly, Douglas M., Jour, George, Bochaca, Irineu Illa, Xia, Yuhe, Johnson, Douglas B., Wheless, Lee, Patrinely, James R., Nomikou, Sofia, Rimm, David L., Pavlick, Anna C., Weber, Jeffrey S., Zhong, Judy, Tsirigos, Aristotelis, Osman, Iman
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7785656/
https://ncbi.nlm.nih.gov/pubmed/33208341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-2415
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