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Evolution of the human mitochondrial ABCB7 [2Fe–2S](GS)(4) cluster exporter and the molecular mechanism of an E433K disease-causing mutation
Iron-sulfur cluster proteins play key roles in a multitude of cellular processes. Iron-sulfur cofactors are assembled primarily in mitochondria and are then exported to the cytosol by use of an ABCB7 transporter. It has been shown that the yeast mitochondrial transporter Atm1 can export glutathione-...
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| Veröffentlicht in: | Arch Biochem Biophys |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7785629/ https://ncbi.nlm.nih.gov/pubmed/33157103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2020.108661 |
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