ABCB10 exports mitochondrial biliverdin, driving metabolic maladaptation in obesity()

Although the role of hydrophilic antioxidants in the development of hepatic insulin resistance and non-alcoholic fatty liver disease (NAFLD) has been well studied, the role of lipophilic antioxidants remains poorly characterized. A known lipophilic H(2)O(2) scavenger is bilirubin, which can be oxidi...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Shum, Michael, Shintre, Chitra A., Althoff, Thorsten, Gutierrez, Vincent, Segawa, Mayuko, Saxberg, Alexandra D., Martinez, Melissa, Adamson, Roslin, Young, Margaret R., Faust, Belinda, Gharakhanian, Raffi, Su, Shi, Krishnan, Karthickeyan Chella, Mahdaviani, Kiana, Veliova, Michaela, Wolf, Dane M., Ngo, Jennifer, Nocito, Laura, Stiles, Linsey, Abramson, Jeff, Lusis, Aldons J., Hevener, Andrea L., Zoghbi, Maria E., Carpenter, Elisabeth P., Liesa, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8300486/
https://ncbi.nlm.nih.gov/pubmed/34011630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.abd1869
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