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Splicing factor SRSF1 limits IFN-γ production via RhoH and ameliorates experimental nephritis
OBJECTIVE: CD4 T helper 1 (Th1) cells producing IFN-γ contribute to inflammatory responses in the pathogenesis of SLE and lupus nephritis. Moreover, elevated serum type II IFN levels precede the appearance of type I IFNs and autoantibodies in patient years before clinical diagnosis. However, the mol...
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| Publicado no: | Rheumatology (Oxford) |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7785303/ https://ncbi.nlm.nih.gov/pubmed/32810232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/keaa300 |
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