A quantitative trait rare variant nonparametric linkage method with application to age-at-onset of Alzheimer’s disease

To analyze pedigrees with quantitative trait (QT) and sequence data, we developed a rare variant (RV) quantitative nonparametric linkage (QNPL) method, which evaluates sharing of minor alleles. RV-QNPL has greater power than the traditional QNPL that tests for excess sharing of minor and major allel...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Eur J Hum Genet
Main Authors: Zhao, Linhai, Zhang, Zhihui, Rodriguez, Sandra M. Barral, Vardarajan, Badri N., Renton, Alan E., Goate, Alison M., Mayeux, Richard, Wang, Gao T., Leal, Suzanne M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7785016/
https://ncbi.nlm.nih.gov/pubmed/32740652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41431-020-0703-z
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados