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A quantitative trait rare variant nonparametric linkage method with application to age-at-onset of Alzheimer’s disease
To analyze pedigrees with quantitative trait (QT) and sequence data, we developed a rare variant (RV) quantitative nonparametric linkage (QNPL) method, which evaluates sharing of minor alleles. RV-QNPL has greater power than the traditional QNPL that tests for excess sharing of minor and major allel...
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| 出版年: | Eur J Hum Genet |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer International Publishing
2020
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7785016/ https://ncbi.nlm.nih.gov/pubmed/32740652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41431-020-0703-z |
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